Detail for Cilofungin
Basic Information
DrugID 26
DrugName Cilofungin
DrugDetail Cilofungin is the first clinically applied member of the Echinocandin family of antifungal drug. It was derived from a fungus in the genus Aspergillus. It accomplishes this by interfering with an invading fungus' ability to synthesize the cell wall (specifically, it inhibits the conversion of lanosterol to ergosterol).

Indication Cilofungin is the Echinocandin family of antifungal drug.

Structure Click to see the orginal picture.
Drug Name PMIDLink Reference
Amphotericin B Hanson LH, Perlman AM, Clemons KV, Stevens DA. (1991) Synergy between cilofungin and amphotericin B in a murine model of candidiasis. Antimicrob Agents Chemother. 35(7):1334-7.
Amphotericin B Sugar AM, Goldani LZ, Picard M. (1991) Treatment of murine invasive candidiasis with amphotericin B and cilofungin: evidence for enhanced activity with combination therapy. Antimicrob Agents Chemother. 35(10):2128-30.
TargetName References EssentialGene? Link
beta-1,3-glucan synthesis inhibitor No
PathWay Name Path Picture